Description
The description
Testosterone tsipionate is one of many esterified versions of testosterone available on the market. It is an injectable form of testosterone with slow release and longer half-life. The release rates of testosterone tsipionate and testosterone enanthate are very similar and the two ingredients are easily interchangeable. For example, during a 10 week cycle with testosterone, testosterone cypionate and testosterone enanthate can be alternated without any problem. Testosterone Cypionate has a half life of around 12 days and Testosterone Enanthate has a half life of around 10 days not much difference.
An interesting fact about Testosterone Cypionate is that it has gained the preference of American bodybuilders over the Enanthate variant. However, its advantage is not great, and the popularity and usage of both options are almost the same. In fact, Testosterone Enanthate will always be a bit more popular. Neither option has advantages over the other.
History of testosterone chipionate
Testosterone Cipionate was first created in the mid-1950s. It was launched in pharmacies by the manufacturer UpJohn under the trade name Testosterone Depot. The name was originally Depot-Testosterone Cyclopentylpropionate, but was abbreviated for obvious reasons. Unlike testosterone enanthate, which was originally distributed worldwide, Cypionate was America's answer to the enanthate variant.
Testosterone Cipionate is so successful that it is still produced by UpJohn (which merged with Pfizer in 2009). Because Testosterone Tsipionate was the American answer to the international Testosterone Enanthate product, many American bodybuilders and athletes in the 1960s, 1970s, and 1980s preferred to use Testosterone Cipionate over the Enanthate option for no reason other than to support the American product. . Again, the Tsipionate and Enanthate variants of testosterone are almost 100% identical and there is no logical reason to prefer one over the other.
There are very few cases of different patients who prefer Testosterone Cipionate over Testosterone Enanthate just because some are more sensitive to injections. A very small percentage reported irritation at the Enanthate variant injection site, with the Cypionate variant found to be more favorable in terms of injection site reaction and comfort.
More information
In medical circles, testosterone cypionate as well as enanthate are mainly used to treat men with androgen deficiency (hypogonadism and andropause).Other, although rare, uses of Testosterone Cypionate in medical settings include: treating people with reduced bone density and strength, treating uncontrolled menstrual bleeding (menorrhagia), treating osteoporosis, treating elderly patients frail and patients after a long period of muscle atrophy. . In recent years, Testosterone Cypionate has been extensively studied for possible use in men, for birth control, in weekly doses of 200mg.
In the 1970s, as with all other anabolic steroids at the time, the approved medical applications of Testosterone Cypionate were curtailed. The Federal Food and Drug Administration has restricted its medical use to the treatment of androgen deficiency in men (hypogonadism and andropause). The case for limiting the use of Testosterone Tsipionate was serious, as testosterone itself is a potent androgen, unsuitable for women and children, where other anabolic steroids (such as Anavar and Primobolan) are more acceptable.
Features of Testosterone Cypionate
As already mentioned, Testosterone Cipionate is simply testosterone with a Cipionate ester attached to its chemical structure. Specifically, Cypionate is cypionic acid, but already bonded to testosterone, in chemistry it is called an ester bond (or ester compound). Zipioic acid is chemically related to the 17-beta hydroxyl group of the testosterone structure.
Esterified anabolic steroids are fat soluble and are slowly released from the injection site. However, this is not the main reason why esters prolong the release and half-life of the anabolic steroid they are attached to.The main reason is that once testosterone tsipionate enters the bloodstream, enzymes begin to bind to the testosterone tsipionate molecule and break the bonds between the ester and the hormone. This takes a different time, depending on the length of ballast. Therefore, longer esters such as cypionate, enanthate, and decanoate have a longer half-life than shorter esters such as propionate, phenylpropionate, and acetate.
Eventually, ester is removed from the hormone by enzymes, leaving only pure testosterone after this chemical reaction. This process of testosterone ester cleavage by enzymes is the real reason for the slower release. Pure testosterone, with no esters attached, has a half-life of around 2-4 hours. When cypionate ester is attached, testosterone cypionate is obtained, in which the half-life of testosterone increases to 12 days, allowing slower release and longer action of the hormone.
Properties of Testosterone Cypionate
The properties and qualities of Testosterone Cypionate are what anyone would expect from any other testosterone product except for the difference in release time and half life. It should be clear to all readers that testosterone is the original and primary anabolic steroid that is produced naturally internally in all humans and most animal species. Two important facts follow from this:
1. Testosterone is used as the primary measure of comparison by which all other anabolic steroids are compared,
2. Because testosterone is a natural anabolic steroid produced by the human body, it is considered the safest anabolic steroid to use. Everyone's body is already accustomed to the effects of testosterone, but to a lesser extent.Testosterone is mainly taken to improve the physique and increase athletic performance.
Application of Testosterone Cypionate
As with almost all Testosterone variants or derivatives, Testosterone Cypionate cycles are primarily used for bulking, to gain muscle mass and to increase strength. While it's ideal for these purposes, that doesn't mean it can't be used effectively (albeit at lower doses) in cleansing cycles. In any case, Testosterone Cypionate is usually given in higher doses (about 500mg per week). The usual dose at this dose is for a period of 12 to 14 weeks, due to its longer ester and therefore longer half-life. Testosterone Cypionate has a half-life of around 10-12 days. In comparison, its analogue Testosterone Enanthate is almost the same, with a half-life of around 7-10 days.
Regardless of the purpose of the cycle, for weight gain or cleansing, Testosterone Cypionate is usually combined with other anabolic steroids that have similar characteristics, for obvious reasons. The usual combination is with an ingredient such as Deca-Durabolin (Nandrolone Decanoate), taken in the same 10-12 weeks with Testosterone Cypionate. Another combination is with a starter ingredient, such as Dianabol (Methandrostenolone), which is included for the first 4-6 weeks.
In the event that Testosterone Cypionate is used during cycles to eliminate or eliminate fat, it can be used as a supporting ingredient, only to maintain the body's natural normal testosterone levels, while the stronger ingredient, more suitable for elimination fats, does the main work.These are the so-called Testosterone Replacement Therapies (TRT), in which the doses of Testosterone Cypionate are around 100mg per week.
Intake and Dosage of Testosterone Cypionate
For medical purposes, Testosterone Cypionate is prescribed at a dose of 250mg taken once every 2-4 weeks depending on the practice of the physician and the progress of the patient in the TRT treatment.
In the field of bodybuilding and to improve athletic performance, Testosterone Cypionate is taken in doses of around 300-500mg per week. The indicated doses are those of introduction. Intermediate doses of Testosterone Cypionate are often between 500-700mg per week. Advanced athletes reach 1000 mg and more per week. If one wants to achieve the best possible results, the ideal option is to take Testosterone Cypionate twice a week, dividing the weekly dose equally.
For example, a weekly dose of Testosterone Cypionate 500mg should be taken 250mg on Monday and 250mg on Thursday, each week. This reduces spikes in blood plasma levels and thus reduces the risk of certain side effects associated with spikes in blood hormone levels.
Testosterone Cypionate Side Effects
In terms of side effects, Testosterone Cypionate can be described as moderate. It is often compared to the almost identical testosterone enanthate. Basically, Cypionate is a variant of testosterone and therefore has all the known side effects of testosterone.
Testosterone is the primary male hormone produced in humans and all vertebrates, making it the father of all anabolic steroids. Of course, when discussing side effects, it should be kept in mind that there are differences between people.They are due to factors such as individual body response, age, sensitivity and genetic predisposition. A lot depends on whether a person will experience a side effect to a greater or lesser extent (or not at all).
Estrogenic
Estrogenic side effects are the first and foremost that almost all anabolic steroid users are aware of. Testosterone itself is a moderately aromatized anabolic steroid (meaning that testosterone is converted (aromatized) into estrogen in the body). The degree of aromatization of Testosterone Cypionate compared to other anabolic steroids is moderate. The degree of aromatization strongly depends on the dosage and, therefore, on the total levels of testosterone in the blood plasma. The rule is that the more testosterone, the more estrogen flavoring. Possible estrogenic side effects include: water retention and bloating, increased blood pressure (due to water retention), increased fat accumulation/retention, and possible development of gynecomastia.
Androgen
Because Testosterone Cypionate is androgenic, androgenic side effects are also possible. Testosterone is reduced in the body to dihydrotestosterone (DHT), a much more potent androgen. To a particularly high degree, this occurs in various tissues the scalp, prostate and skin. This is where most androgenic side effects come from, not the direct interaction of testosterone with androgen receptors. Possible androgenic side effects include: oily skin (sebum secretion), acne (associated with sebum secretion), body and facial hair, and increased risk of baldness if the individual is genetically predisposed.
Hepatotoxicity
As with Enanthate, Testosterone Cypionate shows no hepatotoxic (liver damaging) effects in the body even at extremely high doses.
Suppression of testosterone
Testosterone Cypionate is an anabolic androgenic steroid. Therefore, it has side effects in terms of suppressing the functions of the hypothalamus, pituitary and testicles. In other words, it causes the natural production of testosterone to stop. Other known possible side effects of Testosterone Cypionate include reduction of good cholesterol (HDL) in the blood.
Profile of Testosterone Cypionate
- (17b-hydroxy-4-androsten-3-one, testosterone base + chipionate ester)
- Formula: C27 H40 O3
- Molecular mass: 412.6112 g/mol
- Molecular mass (base): 288.429 g/mol
- Molecular mass (ester): 132.1184 g/mol
- Formula (base): C19 H28 O2
- Formula (ester): C8 H14 O2
- Melting point (base): 155 C
- Melting point (ester): 98,104 C
- Effective dose (men): 300-2000 mg per week
- Effective dose (women): not recommended (androgen)
- Duration of action: 12-14 days
- Trace detection: 3-4 months
- Anabolic / Androgenic Ratio: 100/100
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